Comparative evaluation of antioxidant activity of 2-alkyl-4-methylphenols and their 6-n-octylaminomethyl derivatives


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Abstract

A series of 2-alkyl-4-methyl-6-n-octylaminomethylphenols (where alkyl is methyl or tert-butyl group, or terpene substituent) was synthesized. A comparative evaluation of the antioxidant properties of the starting alkyl- and terpenylphenols and their Mannich bases was carried out using in vitro assays. Structural features providing high antioxidant activity of these compounds were revealed.

About the authors

E. V. Buravlev

Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences

Author for correspondence.
Email: eugeneburavlev@gmail.com
Russian Federation, 48 ul. Pervomaiskaya, Syktyvkar, 167000

I. V. Fedorova

Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences

Email: eugeneburavlev@gmail.com
Russian Federation, 48 ul. Pervomaiskaya, Syktyvkar, 167000

O. G. Shevchenko

Institute of Biology, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences

Email: eugeneburavlev@gmail.com
Russian Federation, 28 ul. Kommunisticheskaya, Syktyvkar, 167982

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