Novel convenient one-pot method for the synthesis of indoloquinolines


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Abstract

A novel one-pot method based on the sequence of the Fisher reaction between nitroacetophenone and phenylhydrazines, the reduction with metallic tin directly in polyphosphoric acid, and acylation has been developed for the synthesis of indoloquinolines. The obtained indolo-[3,2-c]quinolines are precursors of the analogs of isocryptolepine alkaloid.

About the authors

N. A. Aksenov

North Caucasus Federal University

Author for correspondence.
Email: radioanimation@rambler.ru
Russian Federation, 1A ul. Pushkina, Stavropol, 355009

A. Z. Gasanova

North Caucasus Federal University

Email: radioanimation@rambler.ru
Russian Federation, 1A ul. Pushkina, Stavropol, 355009

G. M. Abakarov

Dagestan State Technical University

Email: radioanimation@rambler.ru
Russian Federation, 70 ul. Imama Shamilya, Makhachkala, 367010

I. V. Aksenova

North Caucasus Federal University

Email: radioanimation@rambler.ru
Russian Federation, 1A ul. Pushkina, Stavropol, 355009

A. V. Aksenov

North Caucasus Federal University

Email: radioanimation@rambler.ru
Russian Federation, 1A ul. Pushkina, Stavropol, 355009

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