电邮这篇文章 Peptide Modulators of ASIC Channels of the Sea Anemone Urticina aff. coriacea (Cuvier, 1798) from the Sea of Okhotsk
- 作者: Gladkikh I.N.1, Kvetkina A.N.1, Kostina E.E.2, Kalina R.S.1, Grebnev B.B.1, Koshelev S.G.3, Kozlov S.A.3, Monastyrnaya M.M.1, Kozlovskaya E.P.1
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隶属关系:
- Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
- Zhirmunsky Institute of Marine Biology, National Scientific Center of Marine Biology, Far East Branch, Russian Academy of Sciences
- Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- 期: 卷 44, 编号 6 (2018)
- 页面: 458-464
- 栏目: Original Papers
- URL: https://bakhtiniada.ru/1063-0740/article/view/184281
- DOI: https://doi.org/10.1134/S1063074018060044
- ID: 184281
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详细
A search for biologically active peptides has been performed in an aqueous extract of the sea anemone Urticina aff. coriacea (Cuvier, 1798) (Actiniidae) from the Sea of Okhotsk. A separation of the peptides by size-exclusion chromatography and subsequent electrophysiological testing have shown that peptides of three fractions can completely inhibit currents of mammalian ASIC1a channels. The sea anemone Urticina aff. coriacea is believed to be a promising source of novel peptides that interact with ASIC channels.
作者简介
I. Gladkikh
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: irinagladkikh@gmail.com
俄罗斯联邦, Vladivostok, 690022
A. Kvetkina
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Vladivostok, 690022
E. Kostina
Zhirmunsky Institute of Marine Biology, National Scientific Center of Marine Biology, Far East Branch,Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Vladivostok, 690041
R. Kalina
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Vladivostok, 690022
B. Grebnev
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Vladivostok, 690022
S. Koshelev
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Moscow, 117997
S. Kozlov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Moscow, 117997
M. Monastyrnaya
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Vladivostok, 690022
E. Kozlovskaya
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
俄罗斯联邦, Vladivostok, 690022
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