The Influence of the Trematode Paragonimus cf. westermani on NO- and HIF-1α-Containing Structures in the Brain of the Crab Eriocheir japonica (De Haan, 1835) Decapoda: Varunidae
- Autores: Kotsyuba E.P.1,2
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Afiliações:
- Zhirmunsky Institute of Marine Biology, National Scientific Center of Marine Biology, Far East Branch, Russian Academy of Sciences
- Far Eastern Federal University
- Edição: Volume 44, Nº 5 (2018)
- Páginas: 383-389
- Seção: Original Papers
- URL: https://bakhtiniada.ru/1063-0740/article/view/184257
- DOI: https://doi.org/10.1134/S1063074018050061
- ID: 184257
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Resumo
The influence of the trematode Paragonimus cf. westermani on the NO- and HIF-1α-containing structures in nerve centers of the brain, depending on degree of infection and behavioral responses, has been studied in the crab Eriocheir japonica (De Haan, 1835). The NO-ergic activity in the brain has been found to increase in crabs with a low level of infection and decrease in individuals with a high level of infection. In addition, an increased HIF-1α-immunoreactivity in neurons and hemocytes of the brain has been detected in crabs that show a high level of infection and modified behavior. The involvement of NO and HIF-1α in the induction of brain tolerance and in the pathological states of the brain formed due to parasitic influences is discussed.
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Sobre autores
E. Kotsyuba
Zhirmunsky Institute of Marine Biology, National Scientific Center of Marine Biology, Far East Branch,Russian Academy of Sciences; Far Eastern Federal University
Autor responsável pela correspondência
Email: epkotsuba@mail.ru
Rússia, Vladivostok, 690041; Vladivostok, 690600
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