CYTOKINES' RESPONSE UNDER SEPSIS AND TRAUMA
- Authors: Zotova N.V.1,2, Gusev E.Y.1,2, Zubova T.E.1
-
Affiliations:
- Institute of Immunology and Physiology of UB RAS
- Auto Federal State Autonomous Educational Institution of Higher Professional Education "Ural Federal University named after the first President of Russia B. N. Yeltsin"
- Issue: Vol 20, No 2 (2017)
- Pages: 336-337
- Section: Articles
- URL: https://bakhtiniada.ru/1028-7221/article/view/120068
- ID: 120068
Cite item
Full Text
Abstract
We detected rates of IL-6, -8, -10, TNF-α, and CRP in plasma of patients with sepsis and polytrauma at 1-2nd and 5-7th days after admission in ICU. All patients were divided into groups with/ without MODS development. A rise in mediator levels in all groups of patients were identified. The maximum of detected increasing was in patients with MODS. There was not a clear cytokines-etiological agent dependence.
About the authors
N. V. Zotova
Institute of Immunology and Physiology of UB RAS; Auto Federal State Autonomous Educational Institution of Higher Professional Education "Ural Federal University named after the first President of Russia B. N. Yeltsin"
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
E. Yu. Gusev
Institute of Immunology and Physiology of UB RAS; Auto Federal State Autonomous Educational Institution of Higher Professional Education "Ural Federal University named after the first President of Russia B. N. Yeltsin"
Email: noemail@neicon.ru
Russian Federation
T. E. Zubova
Institute of Immunology and Physiology of UB RAS
Email: noemail@neicon.ru
Russian Federation
References
- Binkowska A. M., Michalak G., Slotwihski R. Current views on the mechanisms of immune responses to trauma and infection. Cent. Eur. J. Immunol. 2015, 40(2), 206-216.
- Черешнев В. А., Гусев Е. Ю., Зотова Н. В. Фундаментально-прикладные аспекты системного воспаления с позиции теории физиологических и типовых патологических процессов. Рос. Физиол. Журн. им. И. М. Сеченова. 2010, 96 (7), 696-707.
- Singer M., Deutschman C. S., Seymour C. W., Shankar-Hari M., Annane D., et al. The Third International Consensus Defi nitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016, 315 (8), 801-810.
Supplementary files
