Translation into Russian of the Classification of inborn errors of immunity in humans updated by experts from a Committee on Congenital Immunity Errors of International Union of Immunological Societies (Russian version 2019)
- Authors: Bolkov M.A.1,2, Tuzankina I.A.1,3, Shinwari K.3, Cheremokhin D.A.1
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Affiliations:
- Research Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences
- Ural State Law University, Ekaterinburg
- Institute of Chemical Engineering, B. Yeltsin Ural Federal University
- Issue: Vol 24, No 1 (2021)
- Pages: 7-68
- Section: INTERNATIONAL DOCUMENTS
- URL: https://bakhtiniada.ru/1028-7221/article/view/120058
- DOI: https://doi.org/10.46235/1028-7221-975-TIR
- ID: 120058
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Abstract
We present to Russian-speaking audience a translation and commentary on the classification of inborn errors of immunity presented at the end of 2019 by the Committee on Congenital Immunity Errors at the International Union of Immunological Societies (IUIS). Inborn errors of immunity, or, as they were called earlier, primary immunodeficiencies, is a rapidly expanding class of diseases that includes the most diverse congenital pathologies which can manifest at any age by heterogenous symptomes. Clinical masks characterize these diseases, hence the time from the onset of clinical disorder to the final diagnosis may take many years. A doctor of any specialty encounters these patients, and the molecular mechanisms of pathology concern different organs and systems of the patients. The classification consists of ten tables covering more than 400 syndromes and their corresponding genes, or associated chromosomal abnormalities. This is a tool, which allows navigating a wide variety of different primary immunodeficiencies, autoimmune and autoinflammatory syndromes, complement defects, and bone marrow failure syndromes. We hope that, due to translation, current knowledge about these various diseases will become more close and available to the Russian-speaking audience.
About the authors
M. A. Bolkov
Research Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences;Ural State Law University, Ekaterinburg
Email: antanariva@gmail.com
ORCID iD: 0000-0003-2763-9907
PhD (Medicine), Senior Research Associate, Research Institute of Immunology and Physiology; Associate Professor, Ural State Law University
Ekaterinburg
Russian FederationI. A. Tuzankina
Research Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences;Institute of Chemical Engineering, B. Yeltsin Ural Federal University
Author for correspondence.
Email: ituzan@yandex.ru
ORCID iD: 0000-0001-7496-0950
Tuzankina Irina A., PhD, MD (Medicine), Professor, Honored Scientist of the Russian Federation, Main Research Associate, Research Institute of Immunology and Physiology; Leading Research Associate, Institute of Chemical Engineering, B. Yeltsin Ural Federal University
620049, Ekaterinburg, Pervomayskaya str., 106.
Russian FederationKh. Shinwari
Institute of Chemical Engineering, B. Yeltsin Ural Federal University
Email: khybershinwari05@gmail.com
ORCID iD: 0000-0002-9800-2797
Shinwari Khyber, Postgraduate Studen
Ekaterinburg
Russian FederationD. A. Cheremokhin
Research Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences
Email: dimacheremokhin@gmail.com
ORCID iD: 0000-0002-3334-2221
Postgraduate Student
Ekaterinburg
Russian FederationReferences
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