CONTENT OF ENDOTHELIAL PROGENITOR CELLS IN UMBILICAL CORD BLOOD IN PREECLAMPSIA
- Authors: Popova I.G.1, Nazarov S.B.1, Kuzmenko G.N.1, Kroshkina N.V.1, Sitnikova O.G.1, Klycheva M.M.1
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Affiliations:
- Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
- Issue: Vol 22, No 2-2 (2019)
- Pages: 897-899
- Section: ORIGINAL ARTICLES
- URL: https://bakhtiniada.ru/1028-7221/article/view/119864
- DOI: https://doi.org/10.31857/S102872210006550-0
- ID: 119864
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Abstract
The content of endothelial progenitor cells in umbilical cord blood was determined in newborns born to mothers with preeclampsia and without preeclampsia. Phenotyping of umbilical cord blood endothelial cells was performed by flow cytometry, circulating endothelial cells (CES) were defined as: CD45–, CD133+, VEGFR2+, CD34–, endothelial progenitor cells (EPCS) were defined as: CD45–, CD133+, VEGFR2+, CD34+. There was a decrease in both the total number of circulating endothelial cells and endothelial progenitor cells in premature infants compared to full-term ones. In newborns born to mothers with preeclampsia, only the number of ECP was significantly higher, compared with newborns from mothers without preeclampsia, and in the group of premature and full-term newborns.
Keywords
About the authors
I. G. Popova
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Author for correspondence.
Email: i_g_popova@mail.ru
candidate of medical Sciences, researcher of clinical biochemistry laboratory, doctor of clinical laboratory diagnostics,
Ivanovo
Russian FederationS. B. Nazarov
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
doctor of medical Sciences, рrofessor, Deputy Director of the Institute for scientific work, head. laboratory of clinical biochemistry and genetics,
Ivanovo
Russian FederationG. N. Kuzmenko
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
doctor of medical Sciences, leading researcher of laboratory of clinical biochemistry, head. clinical diagnostic laboratory,
Ivanovo
Russian FederationN. V. Kroshkina
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
candidate of biology, researcher at the laboratory of clinical immunology,
Ivanovo
Russian FederationO. G. Sitnikova
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
candidate of biology, senior researcher of clinical biochemistry and genetics,
Ivanovo
Russian FederationM. M. Klycheva
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
researcher of clinical biochemistry laboratory,
Ivanovo
Russian FederationReferences
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