INFLUENCE OF CYTOKINES ON BIOFILM FORMATION OF INTESTINAL MICROSYMBIONTS
- Authors: Chainikova I.N.1,2, Ivanova E.V.1,2, Bondarenko T.A.1, Perunova N.B.1, Chelpachenko O.E.1, Nikiforov I.A.1
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Affiliations:
- FGBUN Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences
- GBOU VPO «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
- Issue: Vol 22, No 2-1 (2019)
- Pages: 626-628
- Section: ORIGINAL ARTICLES
- URL: https://bakhtiniada.ru/1028-7221/article/view/120323
- DOI: https://doi.org/10.31857/S102872210006995-9
- ID: 120323
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Abstract
The multidirectional effect of recombinant cytokines (TNF-α, IL-10) on the biofilm formation of intestinal microsymbionts was established, which depended on the concentration of cytokines, the type and strain of microorganisms.
Keywords
About the authors
I. N. Chainikova
FGBUN Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences;GBOU VPO «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
Author for correspondence.
Email: inchainicova@yandex.ru
M.D., professor, Leading Researcher Institute of Cellular and Intracellular Symbiosis;
Professor of the Department of Normal Physiology,
Orenburg
Russian FederationE. V. Ivanova
FGBUN Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences;GBOU VPO «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
MD, Leading Researcher Institute of Cellular and Intracellular Symbiosis;
docent of the Department of Pharmaceutical Chemistry,
Orenburg
Russian FederationT. A. Bondarenko
FGBUN Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences
Researcher Institute of Cellular and Intracellular Symbiosis,
Orenburg
Russian FederationN. B. Perunova
FGBUN Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences
MD, Professor of the Russian Academy of Sciences, Head of the Laboratory of Biomonitoring and Molecular Genetic Research,
Orenburg
Russian FederationO. E. Chelpachenko
FGBUN Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences
M.D., Leading Researcher Institute of Cellular and Intracellular Symbiosi,
Orenburg
Russian FederationI. A. Nikiforov
FGBUN Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences
Ph. D., Leading Researcher Institute of Cellular and Intracellular Symbiosi,
Orenburg
Russian FederationReferences
- Högbom M., Ihalin R. Functional and structural characteristics of bacterial proteins that bind host cytokines. Virulence. 2017, 8(8), 1592–1601.
- Lee J-H, Sorbo L., Khine A. A., Azavedo J., Low D. E., Bell D., Uhlig S., Slutsky A. S., Zhang H. Modulation of Bacterial Growth by Tumor Necrosis Factor-α In Vitro and In Vivo. American Journal of Respiratory and Critical Care Medicine. 2003, 168 (12), 1462–1470.
- O’Toole G.A., Kolter R. Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis. Mol. Microbiol. 1998, 28 (3), 449–61.
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