REACTION OF IMMUNOCOMPETENT CELLS TO KIDNEY ALTERATION IN EXPERIMENTAL ALLOXAN DIABETES
- Authors: Blinkova N.B.1, Danilova I.G.1, Gette I.F.1, Bulavintseva T.S.1
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Affiliations:
- Ural Federal University, Institute of Immunology and physiology UB RAS
- Issue: Vol 20, No 2 (2017)
- Pages: 257-258
- Section: Articles
- URL: https://bakhtiniada.ru/1028-7221/article/view/119803
- ID: 119803
Cite item
Abstract
The reaction of immunocompetent cells to renal alteration was studied on the model of alloxan diabetes in rats. The growing structural violations in the kidney in a chronic hyperglycemia accompanied by increased migration of leukocytes, T-lymphocytes and a decrease in the number of B-lymphocytes and macrophages in the stroma of the organ.
About the authors
N. B. Blinkova
Ural Federal University, Institute of Immunology and physiology UB RAS
Author for correspondence.
Russian Federation
I. G. Danilova
Ural Federal University, Institute of Immunology and physiology UB RASRussian Federation
I. F. Gette
Ural Federal University, Institute of Immunology and physiology UB RASRussian Federation
T. S. Bulavintseva
Ural Federal University, Institute of Immunology and physiology UB RASRussian Federation
References
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- Chow F. Y., Nikolic-Paterson D.J., Atkins R. C., Tesch G. H. Macrophages in streptozotocin-in-duced diabetic nephropathy: potential role in renal fibrosis. Nephrol. Dial. Transplant, 2004, 19, 2987-2996.
- Danilova I. G., Sarapultsev P. A., Medvedeva S. U. Morphological restructuring of myocardium during the early phase of experimental diabetes mellitus. Anat. Rec. (Hoboken), 2015, 298(2), 396-407.
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