CLINICAL ROLE OF LOCAL ANTIMICROBIAL FACTORS AND CYTOKINES IN CHILDREN WITH REACTIVE ARTHRITIS

Cover Page

Cite item

Abstract

Significant local antimicrobial factors of the intestinal biotope and cytokines associated with the variant of the course of reactive arthritis (ReA): IL-17, IL-6, INF-γ, lysozyme, CRB have been determined, which allows them to be used as markers for predicting the course and the outcome of ReA.

About the authors

E. I. Danilova

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

Author for correspondence.
Russian Federation

I. A. Nikiforov

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

Russian Federation

O. E. Chelpachenko

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

Russian Federation

L. P. Fedotova

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

Russian Federation

E. V. Ivanova

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

Russian Federation

N. B. Perunova

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

Russian Federation

T. A. Bondarenko

Institute of Cellular and Intracellular Symbiosis, Ural Branch of the Russian Academy of Sciences

Russian Federation

References

  1. Scher J. U., Littman D.R., Abramson S. B. Microbiome in inflammatory arthritis and human rheumatic diseases. Arthritis Rheumatol.2016, 68(1), 35-45.
  2. Vitetta L., Coulson S., Linnane A. W. et al. The gastrointestinal microbiome and musculoskeletal diseases: a beneficial role for probiotics and prebiotics. Pathogens 2013, 2, 606-626.
  3. O’Hara A.M., Shanahan F. Thegut flora as a forgotten organ. EMBO Rep. 2006, 7, 688-693.
  4. Челпаченко О.Е., Перунова Н.Б., Иванова Е. В. и со-авт. Локальные антимикробные факторы у детей с реактивным артритом. Российский иммунологический журнал 2016, 10(19), 2(1), 372-374.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2017 Danilova E.I., Nikiforov I.A., Chelpachenko O.E., Fedotova L.P., Ivanova E.V., Perunova N.B., Bondarenko T.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).