Pathogenetic aspects of aseptic peri-implant and paraprosthetic complications in traumatology (review)

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Abstract

The use of metal implants and joint prosthetics occupy an important place in modern traumatology and orthopedics. With the increasing proportion of surgical methods for treating bone fractures and joint diseases, complications develop more frequently. Along with early and late wound infections, there are various response changes in tissues in the area of the implant of an abacterial nature. The results of clinical and experimental studies in the development of fibro-proliferative, immuno-allergic and granulomatous tissue changes around implants determine the important role of macrophages, fibroblasts, cells of the immune system, the peculiarities of the pathophysiology of which this article is devoted to.

About the authors

Natalia A. Barkhatova

South Ural State Medical University

Email: barhatova.2020@mail.ru
ORCID iD: 0000-0002-6069-4433
SPIN-code: 5792-8909

MD, Dr. Sci. (Med.), professor, surgeon

Russian Federation, Chelyabinsk

Anton S. Kiselev

City Clinical Hospital N 1

Author for correspondence.
Email: kiselevtrauma@gmail.com

traumatologist-orthopedist

Russian Federation, Chelyabinsk

Ivan S. Kiselev

South Ural State Medical University

Email: kiselevvano@mail.ru

student

Russian Federation, Chelyabinsk

Ekaterina I. Barkhatova

South Ural State Medical University

Email: barhatova_katya_75@mail.ru

student

Russian Federation, Chelyabinsk

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