电邮这篇文章 Prevention of Thromboembolic Complications afterSurgical Treatment for Lower Extremity BoneFractures: Experience in Rivaroxaban Use in ClinicalPractice
- 作者: Kaplunov O.A1, Biryukov S.N1, Nekrasov E.Y.1
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隶属关系:
- Volgograd State Medical University, Volgograd
- 期: 卷 23, 编号 2 (2016)
- 页面: 57-61
- 栏目: Original study articles
- URL: https://bakhtiniada.ru/0869-8678/article/view/47348
- DOI: https://doi.org/10.17816/vto201623257-61
- ID: 47348
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Comparative evaluation of rivaroxaban (main group, n=37) and enoxaparin (control group, n=29) safety in thromboprophylaxis at closed lower extremity bone fractures treatment was performed. All patients were operated on at terms from 8 to 12 day after injury using external fixation devices. The volume of intra- and perioperative blood loss in the groups did not differ significantly ( p >0.05). The rate of symptomatic thromboembolic complications, i.e. calf deep vein thrombosis confirmed by clinical data, was significantly lower in patients from the main group (2.7%) as compared to the control group (6.8%; p <0.05). No one case of clinically important pulmonary embolism was diagnosed. The obtained data showed that in comparable with enoxaparin clinical efficacy for prevention of venous thromboembolic complications the use of rivaroxaban ensured the better clinical safety, convenience of intake and completeness of prophylaxis scheme without the change of pharmacological support.
作者简介
O. Kaplunov
Volgograd State Medical University, Volgograd
Email: volortho@mail.ru
доктор мед. наук,профессор кафедры травматологии, ортопедии и ВПХ; зав. ортопедическим отделением ГКБ №3; Тел.: +7 (8442) 23-45-52. 400005, Волгоград, ул. Советская, д. 45
S. Biryukov
Volgograd State Medical University, Volgogradаспирант кафедры травматологии, ортопедии и ВПХ
E. Nekrasov
Volgograd State Medical University, Volgogradклинический ординатор кафедры травматологии, ортопедии и ВПХ
参考
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