电邮这篇文章 Oxidative stress and inflammation in COVID-19 pathogenesis
- 作者: Kukes V.G.1,2, Parfenova O.K.2, Sidorov N.G.2,3, Olefir Y.V.1, Gazdanova A.А.2
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隶属关系:
- Scientific Centre for Expert Evaluation of Medicinal Products
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- I.I. Mechnikov Research Institute of vaccines and serums
- 期: 卷 26, 编号 4 (2020)
- 页面: 244-247
- 栏目: Reviews
- URL: https://bakhtiniada.ru/0869-2106/article/view/46603
- DOI: https://doi.org/10.17816/0869-2106-2020-26-4-244-247
- ID: 46603
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详细
This study discusses the role of oxidative stress and inflammation in the development of severe acute respiratory syndrome (SARS) associated with COVID-19 caused by the novel SARS-CoV-2 coronavirus. An analysis of the literature revealed that the development of respiratory viral infections, including COVID-19, is usually accompanied by the accumulation of acidic metabolic products in the blood and tissues and, accordingly, oxidative stress and increased levels of cytokines. In this regard, it seems appropriate to use the second-generation low-toxic antioxidant Ethoxidol, manufactured in Russia, which reduces the intensity of inflammation, and also improves blood oxygen saturation.
作者简介
Vladimir Kukes
Scientific Centre for Expert Evaluation of Medicinal Products; I.M. Sechenov First Moscow State Medical University (Sechenov University)
编辑信件的主要联系方式.
Email: elmed@yandex.ru
ORCID iD: 0000-0002-5112-6928
doctor of medical sciences, Professor, Academician, Chief Science Officer “Scientific Centre for Expert Evaluation of Medicinal Products”; Professor, Department of Clinical Pharmacology “I.M. First Moscow State Medical University (Sechenov University)”
俄罗斯联邦, MoscowOlga Parfenova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: oparfenova22@gmail.com
ORCID iD: 0000-0002-0079-2832
俄罗斯联邦, Moscow
Nikita Sidorov
I.M. Sechenov First Moscow State Medical University (Sechenov University); I.I. Mechnikov Research Institute of vaccines and serums
Email: deel@yandex.ru
ORCID iD: 0000-0003-1257-8718
俄罗斯联邦, Moscow
Yuri Olefir
Scientific Centre for Expert Evaluation of Medicinal Products
Email: olefir@expmed.ru
ORCID iD: 0000-0001-7652-4642
MD, PhD, DSc
俄罗斯联邦, MoscowAlbina Gazdanova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: gaa71@bk.ru
ORCID iD: 0000-0001-7099-4547
MD, PhD
俄罗斯联邦, Moscow参考
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- Kukes V.G., Parfenova O.K., Romanov B.K., Prokof’ev A.B., Parfenova E.V., Sidorov N.G. et al. The mechanism of action of ethoxidol on oxidative stress indices in heart failure and hypotension. Sovremennye tekhnologii v meditsine. 2020;12(2):67-73. (in Russian) doi: 10.17691/stm2020.12.2.08.
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