Method of Synthesis of Quinoline Derivatives Based on Ethyl-3-(4-Methyl-2-Oxo-1,2-Dihydroquinoline-3-yl)Propanoates

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Abstract

A convenient and accessible method was used to synthesize novel heterocyclic hybrid systems: 3-(2-(1H-benzo[d]imidazol-2-yl)ethyl)-4-methylquinolin-2(1H)-ones, 3-(2-(benzo[d]oxazol-2-yl)ethyl)-4-methylquinolin-2(1H)-ones, and 3-(2-(benzo[d]thiazol-2-yl)ethyl)-4-methylquinolin-2(1H)-ones. The synthesis was carried out by reacting ethyl 3-(4-methyl-2-oxo-1,2-dihydroquinolin-3-yl)propanoates, substituted in the benzene ring, with α-phenylenediamine, α-aminophenol, and α-aminobenzenedithiol.

About the authors

I. L. Aleksanyan

Yerevan State University

Email: aleksanyan@ysu.am
ORCID iD: 0000-0002-4039-2323
Armenia, Yerevan

L. P. Hambardzumyan

Yerevan State University

ORCID iD: 0000-0003-1210-0052
Armenia,Yerevan

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