2-(2-Methoxyphenyl)-1-Methylcyclohexan-1-Ols in the Ritter Reaction

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Abstract

The Ritter reaction of 2-(2-methoxyphenyl)-1-methylcyclohexan-1-ols with various nitriles was investigated. Depending on the nature of the nitrile and the substituents on the 2-methoxyphenyl fragment of the alcohols, the reaction can lead to both N-(2-(2-methoxyphenyl)-1-methylcyclohexyl)amides and derivatives of partially hydrogenated spiroindolenines in a diastereoselective manner.

About the authors

Y. S Rozhkova

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

Email: rjs@mail.ru
ORCID iD: 0000-0002-4014-3503
Perm, Russia

A. S Pegushina

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

ORCID iD: 0009-0003-3610-4346
Perm, Russia

O. A Mayorova

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

ORCID iD: 0009-0000-8873-4444
Perm, Russia

V. V Morozov

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

ORCID iD: 0000-0003-2318-5338
Perm, Russia

Y. V Shklyaev

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

ORCID iD: 0000-0001-7016-1190
Perm, Russia

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