Diastereoselective Synthesis of Partially Hydrogenated Derivatives of Xantheno[9,8a-b]Indole and Benzo[d]Naphtho[1,8-ab]Carbazol-4-One

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Abstract

Diastereoselective synthesis of 1,2,3,4,4a,14a-hexahydro-8aH-xanthenone[9,8a-b]indole and 3,4b,5,6,7,8,8a,15b-octahydro-4H-benzo[d]naphtho[1,8-ab]carbazol-4-one derivatives has been developed based on a domino sequence that involves electrophilic ortho-spirodearomatization via the Ritter reaction and intramolecular nucleophilic trapping of spiro-σ-intermediates.

About the authors

Y. S Rozhkova

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

Email: rjs@mail.ru
ORCID iD: 0000-0002-4014-3503
Perm, Russia

V. V Morozov

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

ORCID iD: 0000-0003-2318-5338
Perm, Russia

A. S Pegushina

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

ORCID iD: 0009-0003-3610-4346
Perm, Russia

Y. V Shklyaev

Institute of Technical Chemistry of the Ural Branch of the Russian Academy of Sciences, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences

ORCID iD: 0000-0001-7016-1190
Perm, Russia

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