Linear IGA-dependent bullous dermatosis in a 2-year-old child
- Authors: Karacheva Y.V.1, Ruksha T.G.1, Naumova A.S.2, Motorina A.V.1
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Affiliations:
- Krasnoyarsk State Medical University
- Cosmetology center “Darling”
- Issue: Vol 98, No 1 (2022)
- Pages: 75-80
- Section: CLINICAL CASE REPORTS
- URL: https://bakhtiniada.ru/0042-4609/article/view/117621
- DOI: https://doi.org/10.25208/vdv1280
- ID: 117621
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Abstract
Linear IgA-dependent bullous dermatosis is a rare subepidermal bladderworm disease that occurs in both adults and children. The pathogenesis of the disease, regardless of age, is the same, where the basis is the autoimmune response to antigens of the basal membrane zones of the skin, the clinical picture in childhood differs from the manifestations at an older age, having a clear picture and localization of manifestations. The causes of the onset of the disease in older people are most often associated with taking medications, manifested as a side effect of the therapy being taken, cancer, and in children, both an acquired character and a genetic predisposition are responsible for the manifestation of linear IgA-dependent bullous dermatosis. The diagnosis can be confirmed by histological and immunofluorescence analysis.
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##article.viewOnOriginalSite##About the authors
Yuliya V. Karacheva
Krasnoyarsk State Medical University
Email: julkar19@yandex.ru
ORCID iD: 0000-0003-2619-9786
SPIN-code: 4789-9178
MD, Dr. Sci. (Med.), assistant professor
Russian Federation, Partizanа Zheleznyakа str., 1, Krasnoyarsk, 660022Tatiana G. Ruksha
Krasnoyarsk State Medical University
Author for correspondence.
Email: tatyana_ruksha@mail.ru
ORCID iD: 0000-0001-8142-4283
SPIN-code: 5412-2148
MD, Dr. Sci. (Med.), Professor
Russian Federation, Partizanа Zheleznyakа str., 1, Krasnoyarsk, 660022Anna S. Naumova
Cosmetology center “Darling”
Email: tatyana_ruksha@mail.ru
ORCID iD: 0000-0002-6766-8430
Russian Federation, Karla Marksa str., 157a, Krasnoyarsk, 660021
Anna V. Motorina
Krasnoyarsk State Medical University
Email: kozlovaa.v@mail.ru
ORCID iD: 0000-0003-2211-1708
SPIN-code: 4368-3288
Cand. Sci. (Med.)
Russian Federation, Partizanа Zheleznyakа str., 1, Krasnoyarsk, 660022References
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