Herpes zoster following COVID-19 vaccination: about 2 cases
- Authors: Ben Salah N.1, Lahouel I.1, Manaa L.1, Soua Y.1, Youssef M.1, Belhadjali H.1, Zili J.1
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Affiliations:
- University of Monastir, Department of Dermatology
- Issue: Vol 98, No 1 (2022)
- Pages: 72-74
- Section: CLINICAL CASE REPORTS
- URL: https://bakhtiniada.ru/0042-4609/article/view/117620
- DOI: https://doi.org/10.25208/vdv1275
- ID: 117620
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Abstract
The COVID-19 vaccine often well tolerated in healthy adults at the same time, different cutaneous reactions have been reported. Two cases presented of developed a first episode of Herpes zoster (HZ) following the first dose of vaccination against COVID-19. The pathogenetic mechanism suggested that SARS-CoV-2 infection can induce a decrease of blood absolute lymphocyte number, especially CD3+ CD8+ lymphocyte. The COVID-19 vaccine, by stimulation of inflammatory cytokines, may negatively affect the antigen expression and contribute to HZ reactivation. It is also possible that the vaccine induces some kind of immunomodulation that allows VZV to revert an infectious state.
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##article.viewOnOriginalSite##About the authors
Nesrine Ben Salah
University of Monastir, Department of Dermatology
Author for correspondence.
Email: nesrinebensalah2612019@gmail.com
Tunisia, Fattouma Bourguiba Hospital Avenue Avicenne — Monastir — 5019
Ines Lahouel
University of Monastir, Department of Dermatology
Email: nesrinebensalah2612019@gmail.com
Tunisia, Fattouma Bourguiba Hospital Avenue Avicenne — Monastir — 5019
Linda Manaa
University of Monastir, Department of Dermatology
Email: nesrinebensalah2612019@gmail.com
Tunisia, Fattouma Bourguiba Hospital Avenue Avicenne — Monastir — 5019
Yosra Soua
University of Monastir, Department of Dermatology
Email: nesrinebensalah2612019@gmail.com
Tunisia, Fattouma Bourguiba Hospital Avenue Avicenne — Monastir — 5019
Monia Youssef
University of Monastir, Department of Dermatology
Email: nesrinebensalah2612019@gmail.com
Tunisia, Fattouma Bourguiba Hospital Avenue Avicenne — Monastir — 5019
Hichem Belhadjali
University of Monastir, Department of Dermatology
Email: nesrinebensalah2612019@gmail.com
Tunisia, Fattouma Bourguiba Hospital Avenue Avicenne — Monastir — 5019
Jameleddine Zili
University of Monastir, Department of Dermatology
Email: nesrinebensalah2612019@gmail.com
Tunisia, Fattouma Bourguiba Hospital Avenue Avicenne — Monastir — 5019
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