PH OF THE TOPICAL DRUG VEHICLE: SELECTING AN OPTIMUM VALUE AND ROLE OF THE BUFFER SYSTEM
- 作者: Dukhanin A.S.1
-
隶属关系:
- Pirogov Russian National Research Medical University
- 期: 卷 92, 编号 2 (2016)
- 页面: 110-114
- 栏目: DRUG TREATMENT IN DERMATOVENEROLOGY
- URL: https://bakhtiniada.ru/0042-4609/article/view/116824
- DOI: https://doi.org/10.25208/0042-4609-2016-92-2-110-114
- ID: 116824
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详细
The following three groups of factors must be taken into consideration for selecting an optimum pH value of a topical drug: pharmaceutical, pharmacological and compatibility factors. To ensure a stable pH value, the drug vehicle comprises different buffer systems: single component and two-component ones. The optimum conditions for selecting and maintaining the vehicle pH were examined by the example of glucocorticosteroid-based topical drugs.
作者简介
A. Dukhanin
Pirogov Russian National Research Medical University
编辑信件的主要联系方式.
Email: das03@rambler.ru
俄罗斯联邦
参考
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