Interphase Distribution of Caffeine and Coumarin in Extraction Systems with Polyethylene Glycol and Sodium Sulfate

Abstract

An environmentally friendly aqueous two-phase system based on polyethylene glycol and sodium sulfate has been proposed for the extraction of caffeine and coumarin. The kinetic dependence of distribution coefficients for caffeine and coumarin in the system under investigation has been obtained. The dependences of the quantitative characteristics of caffeine and coumarin extraction on the acidity of the medium, the concentrations of the polymer and phase-forming salt, temperature, and the molecular weight of the polymer have been found. The results of this study can be used in the development of effective chemical processes that meet green chemistry requirements.