Optimal Process Parameters of the Synthesis of Lactic Acid by Continuous Fermentation

Abstract

A generalized mathematical model has been used to assess the technological parameters of the continuous fermentation process of preparation of lactic acid under optimal conditions. The model takes into account all types of inhibition, such as inhibition by the biomass, substrate, and product. Equations for calculating the process parameters have been obtained that are included in the calculation sequence algorithm. The algorithm peculiarities include the requirement of supplementing the raw data by the data obtained during the calculation process (interactive mode). The algorithm takes into account the necessary restrictions, noncompliance with which may lead to the results that do not meet the conditions required to implement the process. For the same value of the production efficiency with respect to the target product, there are multiple values of the S₀^s and M₀^s starting parameters (concentration values at the fermenter entry) under the optimal conditions. Limits of the multiplicity existence have been determined. The numerical values of the constants given in the scientific literature for studying the particular mathematical models have been used in the practical calculations.