Formation and Properties of Multilayer Films Based on Polyethyleneimine and Bovine Serum Albumin
- Авторы: Kulikouskaya V.I.1, Lazouskaya M.E.1, Kraskouski A.N.1, Agabekov V.E.1
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Учреждения:
- Institute of Chemistry of New Materials
- Выпуск: Том 92, № 1 (2018)
- Страницы: 146-152
- Раздел: Physical Chemistry of Surface Phenomena
- URL: https://bakhtiniada.ru/0036-0244/article/view/169870
- DOI: https://doi.org/10.1134/S0036024418010132
- ID: 169870
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Аннотация
(Polyethyleneimine/bovine serum albumin)n ((PEI/BSA)n) multilayer films (n = 1–10) are produced via the layer-by-later deposition of polyelectrolytes. It is shown that thickness and morphology of the formed coatings can be controlled by varying the solution’s ionic strength during alternating adsorption of the components. (PEI/BSA)10 multilayer systems that contain up to 0.6 mg of antiseptic miramistin per 1 cm2 of film were created. It is established that the kinetics of miramistin release from (PEI/BSA)10 films in phosphate buffers and physiological solutions obey the Korsmeyer–Peppas equation with a high degree of accuracy (R2 > 0.95).
Об авторах
V. Kulikouskaya
Institute of Chemistry of New Materials
Автор, ответственный за переписку.
Email: kulikouskaya@gmail.com
Белоруссия, Minsk, 220141
M. Lazouskaya
Institute of Chemistry of New Materials
Email: kulikouskaya@gmail.com
Белоруссия, Minsk, 220141
A. Kraskouski
Institute of Chemistry of New Materials
Email: kulikouskaya@gmail.com
Белоруссия, Minsk, 220141
V. Agabekov
Institute of Chemistry of New Materials
Email: kulikouskaya@gmail.com
Белоруссия, Minsk, 220141
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