Study on metronidazole distribution in rectal cancer tissue using application method of administration in experiment in vivo

S. A. Yagubov; G. M. Yankovskii; S. E. Kondakov

doi:10.3103/S0027131416050138

Study on metronidazole distribution in rectal cancer tissue using application method of administration in experiment in vivo

作者: Yagubov S.A.¹, Yankovskii G.M.¹, Kondakov S.E.²
隶属关系:
1. Blokhin Russian Cancer Research Center
2. Department of Chemistry
期: 卷 71, 编号 5-6 (2016)
页面: 312-318
栏目: Article
URL: https://bakhtiniada.ru/0027-1314/article/view/163325
DOI: https://doi.org/10.3103/S0027131416050138
ID: 163325

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详细

The distribution of metronidazole in rectal cancer tissue using application method of administration was studied. A comparative evaluation of pharmacokinetic parameters of metronidazole accumulation in the tissues depending on the concentration of the drug in the application mixture was carried out. The generalized actual data on metronidazole distribution in tissue samples (341 sample) obtained during 31 surgery are presented.