Email this article PEG-Chitosan as a Perspective Stabilizing Agent for Liposomal Suspensions: The Influence of the Molecular Weight and Degree of PEGylation on the Physicochemical Properties of the Complex
- Authors: Le-Deygen I.M.1, Kudryashova E.V.1
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Affiliations:
- Department of Chemistry
- Issue: Vol 73, No 2 (2018)
- Pages: 69-73
- Section: Article
- URL: https://bakhtiniada.ru/0027-1314/article/view/163624
- DOI: https://doi.org/10.3103/S0027131418020074
- ID: 163624
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Abstract
The possibility of regulating the physicochemical properties (stability, size, and binding sites) of liposomal containers for drug delivery by selecting the molecular weight and degree of modification of PEG-chitosan is demonstrated. The effect of the regulation of the release of doxorubicin from liposomal containers depending on the properties of the polymer and pH is demonstrated.
About the authors
I. M. Le-Deygen
Department of Chemistry
Author for correspondence.
Email: i.m.deygen@gmail.com
Russian Federation, Moscow, 119991
E. V. Kudryashova
Department of Chemistry
Email: i.m.deygen@gmail.com
Russian Federation, Moscow, 119991
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