Email this article High throughput screening platform for new inhibitors of protein biosynthesis
- Authors: Sergiev P.V.1, Osterman I.A.1, Golovina A.Y.1, Andreyanova E.S.1, Laptev I.G.1, Pletnev F.I.1, Evfratov S.A.1, Marusich E.I.2, Veselov M.S.2, Leonov S.V.2, Ivanenkov Y.A.2, Bogdanov A.A.1, Dontsova O.A.1
-
Affiliations:
- Department of Chemistry
- Moscow Institute of Physics and Technology (State University)
- Issue: Vol 71, No 1 (2016)
- Pages: 65-67
- Section: Article
- URL: https://bakhtiniada.ru/0027-1314/article/view/163151
- DOI: https://doi.org/10.3103/S0027131416010144
- ID: 163151
Cite item
Open Access
Access granted
Subscription Access
Abstract
The search for new antibiotics is an important task, which is of interest for both basic research and health care practices. It is essential to elucidate the mechanism of antimicrobial action during the screening for antimicrobial activity and at the same time be able to test thousands of compounds. A robotic screening system for potential antibiotics developed at the Department of Chemistry at Moscow State University has been described that enables the immediate identification of those that inhibit protein biosynthesis.
Keywords
About the authors
P. V. Sergiev
Department of Chemistry
Author for correspondence.
Email: petya@genebee.msu.ru
Russian Federation, Moscow
I. A. Osterman
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
A. Ya. Golovina
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
E. S. Andreyanova
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
I. G. Laptev
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
F. I. Pletnev
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
S. A. Evfratov
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
E. I. Marusich
Moscow Institute of Physics and Technology (State University)
Email: petya@genebee.msu.ru
Russian Federation, Moscow
M. S. Veselov
Moscow Institute of Physics and Technology (State University)
Email: petya@genebee.msu.ru
Russian Federation, Moscow
S. V. Leonov
Moscow Institute of Physics and Technology (State University)
Email: petya@genebee.msu.ru
Russian Federation, Moscow
Ya. A. Ivanenkov
Moscow Institute of Physics and Technology (State University)
Email: petya@genebee.msu.ru
Russian Federation, Moscow
A. A. Bogdanov
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
O. A. Dontsova
Department of Chemistry
Email: petya@genebee.msu.ru
Russian Federation, Moscow
Supplementary files
