Electrochemical Oxidation of Difenoconazole in Solutions: LC/MS Identification of Reaction Products

Abstract

Electrochemical transformation of difenoconazole (3-chloro-4-((2RS,4RS;2RS,4SR)-4-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl)phenyl 4-chlorophenyl ether) is studied in mixed-aqueous solvents (a mixture of aqueous ammonium formate (pH = 7.4) and acetonitrile (ACN) in a volume ratio of 3 : 1); the difenoconazole solution’s concentration is 100 μg/mL. The products are analyzed by chromatography–mass spectroscopy (HPLC/ESI MS/MS). Many of the products of difenoconazole electrochemical transformations result from oxidation involving the aliphatic part of the molecule.