Studying Dependences Between the Chemotype Structure of Some Natural Compounds and the Spectrum of Their Targeted Activities Correlated with the Hypoglycemic Effect


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Resumo

The method of similarity to standards is used to calculate the spectrum of targeted hypoglycemic activities of a series of natural compounds of terpenoid and polyphenol classes. Some compounds are shown to be promising multitargeted hypoglycemic agents. Primary action targets are identified.

Sobre autores

P. Vasilyev

Volgograd State Medical University

Email: luzina@nioch.nsc.ru
Rússia, Volgograd

O. Luzina

Vorozhtsov Institute of Organic Chemistry, Siberian Branch

Autor responsável pela correspondência
Email: luzina@nioch.nsc.ru
Rússia, Novosibirsk

D. Babkov

Volgograd State Medical University

Email: luzina@nioch.nsc.ru
Rússia, Volgograd

D. Appazova

Volgograd State Medical University

Email: luzina@nioch.nsc.ru
Rússia, Volgograd

N. Salakhutdinov

Vorozhtsov Institute of Organic Chemistry, Siberian Branch; Novosibirsk State University

Email: luzina@nioch.nsc.ru
Rússia, Novosibirsk; Novosibirsk

A. Spasov

Volgograd State Medical University

Email: luzina@nioch.nsc.ru
Rússia, Volgograd

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