Vanillylmindalic acid excretion in patients with coronary heart disease

Daily urinary excretion of vanillylmindalic acid in patients with acute myocardial infarction and progressive angina pectoris was studied in dynamics. We examined 110 patients on days 1-5, 6-10, 30-35 of the disease (group I). There were 76 men, aged 32-84 years (mean age, 56.0), and 34 women, aged 44-85 years (mean age, 66.3). Large focal myocardial infarction was diagnosed in 69 (62.7%) patients, small focal - in 18 (16.4%), recurrent - in 23 (20.9%). Myocardial infarction of anterior wall of the left ventricle was diagnosed in 64 patients, posterior - in 32 patients, and anteroposterior - in 14 patients. Acute period of the disease occurred in 66 (60%) patients with various complications: cardiac rhythm and conduction disorders, circulatory disorders, pulmonary edema, 1st-II degree cardiogenic shock, thromboembolism, acute atony of the stomach and intestines, cardiac asthma.