Exocrine function of the pancreas in peptic ulcer disease

Questions related to the study of the function of the pancreas in gastric ulcer and duodenal ulcer cannot be considered finally resolved, since the available literature data are contradictory. Some authors [1, 12] observed an increase in the enzymatic activity of the pancreas in peptic ulcer disease, proceeding with increased secretion, others [11, 14] do not note such a pattern. There is no consensus on the nature of disorders of the enzymatic activity of the pancreas in peptic ulcer disease. V. T. Pozdnyakov, Ya. S. Zimmerman, and others believe that this predominantly affects the amylolytic function; according to Z. V. Smirnova, E. N. Nechaev and others, the lipolytic activity of pancreatic juice is mainly affected; according to O. G. Gogiberidze, A. M. Kostyukov, A. I. Venner, frustration of tryptic function is more often observed.