Calmette. Tuberculosis virus, prebacillary granules and bacillosis (Pr. med. 1930, No. 23)

Calmette. Tuberculosis virus, prebacillary granules and bacillosis (Pr. med. 1930, No. 23). The discovery by Fontés (1910) of invisible filterable virulent elements in tuberque. This was disputed and ignored until 1923 . Since that time and after the work of Vandremer Calmette, he has undertaken a number of experimental works, as a result of which he proposed the term tuberculosis ultravirus, the presence of invisible virulent filterable elements in organs, pus, sputum, blood, urine, milk, in the pleurisy. gray-fib-rin. effusions and also in young cultures of Koch bacilli; the passage of these elements through the placenta, infection and intoxication of newborns with these filtered elements, which were hardly cultivated only on vitamin-rich media, and gave in these cultures a toxin very active and labile, from tuberculins; the action of this toxin should be attributed to "unexplained deaths" and progressive emaciation, so frequent in the first weeks after childbirth in children from tubal mothers.