To the mechanism of action of novocaine blocades of the intestinal nerves on motor activity of the small intestinal in experimental peritonitis

The question of restoring the tone of the intestinal muscles after operations in the abdominal cavity and with inflammatory phenomena in it still remains unresolved. Discussing the mechanism of development of intestinal paresis in peritonitis, the authors usually pay attention to the state of the nervous system, especially its vegetative part, as directly responsible for the regulation of the tone of smooth muscle organs. Recognizing the violation of the tone of the autonomic nervous system in peritonitis, researchers often come, however, to contradictory judgments about the degree of damage to its parts. So, M. K. Avdeev and D. I. Vyropaev (1936), L. V. Lepeshinsky (1940), S. S. Girgolav and V. S. Levit (1946), N. L. Gurevich (1951), V. Ya. Shlapobersky (1958), Ya. Nelyubovich (1961) and others attribute the occurrence of intestinal paresis due to damage, mainly, of the parasympathetic division of the autonomic nervous system. A whole number of authors associate the occurrence of intestinal paresis with changes in the sympathetic section of the autonomic nervous system (B. G. Rubinstein, 1936; S. M. Muromtsev, 1938; G. M. Shpolyansky, 1939, 1945; I. F. Pantsevich, 1948 ; and etc.). Such inconsistency of data in understanding the mechanism of intestinal paresis during the development of an inflammatory process in the abdominal cavity significantly limits the scope of rational therapeutic treatment of this formidable complication.