Immunologic peculiarities of the diagnosis and course prediction of pulmonary diseases of professional etiology
- Authors: Kosarev V.V.1, Zhestkov A.V.1, Lotkov V.S.1
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Affiliations:
- Samara State Medical University
- Issue: Vol 80, No 5 (1999)
- Pages: 364-368
- Section: Articles
- URL: https://bakhtiniada.ru/kazanmedj/article/view/70187
- DOI: https://doi.org/10.17816/kazmj70187
- ID: 70187
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Abstract
The work to improve early diagnosis of professional pulmonary diseases and prediction of theis course using current estimation methods of cellular and humoral links of the immune system was carried out. It is istablished that the changes, intensity and nature of which depend on fibrogenety of dust particles, develop in the immune system of workers in the process of contact with industrial aerosols. The tendency to forming secondary immunodeficient state is revealed. The pronounced increase of fibronectin is found in the analysis of nonspecific organism defense mechanisms. In chronic dioxine action the macrophagal — neutrophilic system is made more active initially, the immune system is involved for the second time.
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##article.viewOnOriginalSite##About the authors
V. V. Kosarev
Samara State Medical University
Author for correspondence.
Email: info@eco-vector.com
Professor, Head of the Department of Occupational Diseases
Russian Federation, SamaraA. V. Zhestkov
Samara State Medical University
Email: info@eco-vector.com
Department of Occupational Diseases
Russian Federation, SamaraV. S. Lotkov
Samara State Medical University
Email: info@eco-vector.com
Department of Occupational Diseases
Russian Federation, SamaraReferences
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