The effectiveness of photodynamic therapy in pediatric practice
- Authors: Osipov S.A.1, Aliev M.A.1, Daribaeva N.A.2, Murtazin A.A.2, Agaeva F.L.3, Khairullina A.A.2, Shalganova K.S.2, Filippova A.A.2, Iksanova V.V.2, Zhidenko M.A.4, Salatov Y.S.5
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Affiliations:
- I.P. Pavlov First St. Petersburg State Medical University
- Bashkir State Medical University
- Samara State Medical University
- Russian University of Medicine
- Far Eastern Federal University
- Issue: Vol 41, No 3 (2024)
- Pages: 60-76
- Section: Review of literature
- URL: https://bakhtiniada.ru/PMJ/article/view/260575
- DOI: https://doi.org/10.17816/pmj41360-76
- ID: 260575
Cite item
Abstract
Photodynamic therapy (PDT) is a relatively young but rapidly developing method of treatment. Currently, PDT is widely used in dentistry, dermatology, oncology and other fields of medicine. Cases of successful treatment of tumors of the head and neck, brain, lungs, pancreas, colon, breast, prostate, bladder, cervix and skin using PDT are described in literature. In addition, the effectiveness of PDT in the treatment of bacterial and fungal infections has been repeatedly proved. To date, there are a large number of studies on the use of PDT in various diseases in adults, but few data on this subject in children. The authors have been searching for publications in the electronic databases PubMed, Google Scholar and eLibrary by the following keywords: "PDT", "photodynamic therapy", "pediatrics", "children", "dermatology", "dentistry", "pulmonology", "ophthalmology", "oncology". The search was conducted from the moment of the foundation of the corresponding database to August 2023. PDT is an innovative method of treating neoplasms and bacterial infections. On the basis of the data obtained while conducting the study, it can be confirmed that applying PDT allows to reduce the number of surgical interventions and achieve the best treatment results. All the studies and clinical cases with the use of PDT in the treatment of various diseases in children, which are presented in this review, demonstrated that the treatment results were better than those with standard therapy. However, certain limitations must be taken into account, these include difficulties in selecting a photosensitizer and its route of administration. At present PDT is being actively studied in the pediatric population, but there are still many gaps that require additional large-scale studies.
Keywords
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##article.viewOnOriginalSite##About the authors
S. A. Osipov
I.P. Pavlov First St. Petersburg State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0005-6516-3446
Postgraduate
Russian Federation, St. PetersburgM. A. Aliev
I.P. Pavlov First St. Petersburg State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0003-9088-8321
Student
Russian Federation, St. PetersburgN. A. Daribaeva
Bashkir State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0009-1979-2208
Student
Russian Federation, UfaA. A. Murtazin
Bashkir State Medical University
Author for correspondence.
Email: olofb@list.ru
ORCID iD: 0009-0001-4491-9495
Assistant
Russian Federation, UfaF. L. Agaeva
Samara State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0000-7001-553X
Student
Russian Federation, SamaraA. A. Khairullina
Bashkir State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0001-0631-9851
Student
Russian Federation, UfaK. S. Shalganova
Bashkir State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0008-0900-8697
Student
Russian Federation, UfaA. A. Filippova
Bashkir State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0005-4075-5664
Student
Russian Federation, UfaV. V. Iksanova
Bashkir State Medical University
Email: olofb@list.ru
ORCID iD: 0009-0004-5867-649X
Student
Russian Federation, UfaM. A. Zhidenko
Russian University of Medicine
Email: olofb@list.ru
ORCID iD: 0000-0002-9330-2117
Student
Russian Federation, MoscowYa. S. Salatov
Far Eastern Federal University
Email: olofb@list.ru
ORCID iD: 0000-0003-1100-1394
Student
Russian Federation, VladivostokReferences
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