The clinical and laboratory characteristic of influenza caused by pandemic strain A H1N1 in pregnant women

Influenza and other acute respiratory viral infections take first place among infectious diseases. The most severe disease was observed in pregnant women dew to changes in immune, respiratory and cardiovascular systems. Pregnant women were hospitalized in the infectious disease clinic where they were examined. Main flu symptoms caused by a pandemic strain A H1N1 virus are fever, intoxication, tracheobronchitis. The average duration of the hectic period consists of 6 ± 1.3 days. The changes in biochemical study were characterized by low levels of blood lactate dehydrogenase (LDH) up to 300 e/l, creatine phosphokinaze (CPK) to 525 e/l. Severe influenza complications as pneumonia were observed in 15 patients (16%). Peculiarities of the severe influenza course is the lack of correlation between the clinical and radiological picture of lung complications, progression of acute respiratory distress syndrome requiring constant respiratory support.

influenza, pneumonia, acute respiratory distress syndrome, pulse oximetry, relenza