Email this article Evaluation of the connective tissue graft with the autologous vascular stromal fraction of lipoaspirate to gingival recession treatment (a 10-year observation)
- Authors: Perova M.D1, Lapina N.V1, Fomicheva E.A.2, Karpyuk V.B3, Tropina A.V2, Vziatyshev A.A2
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Affiliations:
- State budgetary educational institution of higher professional education «Kuban State Medical University»
- Municipal budgetary health-care institution Dental polyclinic №3
- Plastic surgery clinic «Chalet Sante»
- Issue: Vol 20, No 5 (2016)
- Pages: 260-266
- Section: Articles
- URL: https://bakhtiniada.ru/1728-2802/article/view/42078
- DOI: https://doi.org/10.18821/1728-28022016;20(5):260-266
- ID: 42078
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Abstract
Material and methods: In present study evaluated long-term results of connective tissue graft with the autologous lipoaspirate vascular stromal fraction (VSF), without the expansion in vitro, in the treatment ofIB and IIB Classes gingival recessions (test group). In the control group the VSF was not used. Thirty-six somatically healthy patients aged 31.4 ± 11.7 years, 105 recession-type defects were available for the 2,6 and 10-year recall. Efficacy parameters included the tissue recession level (TR), the probing depth of gingival sulcus (PD), width of keratinized gingiva (KTw), clinical attachment level (CAL), percentage of root coverage (RC) and patient esthetically satisfaction were detected. Results: After 10 years, the achieved level of root coverage at 80-100% was detected in 46 of 52 cases in the test, and in 11 cases out of 37 in the control group. The KTw in the test group was 6.3 mm vs 4.9 mm in the control group. CAL was remained at the achieved level (5.1 mm), as for the control group, the regression of this parameterfrom 2.8 mm in 2 years to 2.0 mm in 10 years. PD remained within normal value throughout the observation period. In addition, the use of VSF capable of modifying the regenerated tissue biotype, which affects the degree of patient satisfaction - 96% satisfied with the results vs 87% in the control. For a long-term research, the negative influence of the residual risk factors to the tissue recessions was detected: in these cases the CAL reduced to 3.5 mm in the test group, and this structure completely regressed in the control group. Conclusions: The use of cellular-assisted surgery to the gingival recession showed a 3-fold greater efficiency. Risk factors for progression of recession-type defects must be detected and corrected prior surgical treatment.
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##article.viewOnOriginalSite##About the authors
M. D Perova
State budgetary educational institution of higher professional education «Kuban State Medical University»Кафедра стоматологии ФПК и ППС ГБОУ ВПО, кафедра ортопедической стоматологии 350063, Krasnodar, Russia
N. V Lapina
State budgetary educational institution of higher professional education «Kuban State Medical University»Кафедра стоматологии ФПК и ППС ГБОУ ВПО, кафедра ортопедической стоматологии 350063, Krasnodar, Russia
Elena Alexandrovna Fomicheva
Municipal budgetary health-care institution Dental polyclinic №3
Email: roman.fomichev@yandex.ru
kand. med. sci., Municipal budgetary health-care institution Dental polyclinic № 3 350078, Krasnodar, Russia
V. B Karpyuk
Plastic surgery clinic «Chalet Sante»350020, Krasnodar, Russia
A. V Tropina
Municipal budgetary health-care institution Dental polyclinic №3350078, Krasnodar, Russia
A. A Vziatyshev
Municipal budgetary health-care institution Dental polyclinic №3350078, Krasnodar, Russia
References
- Palmer R.M., Cortellini P. Group B of European Workshop on Periodontology. Periodontal tissue engineering and regeneration: Consensus Report of the Sixth European Workshop on Periodontology. J. Clin. Periodontol. 2008; 35(8): 86-3.
- Newman M.G., Takei H.H., Klokkevold P.R., Carranza F.A. Carranza′s Clinical Periodontology. Middle East and African Edition, 10th Ed. St. Louis: Saunders Elsevier; 2007.
- Вольф Г., Ратейцхак Э., Ратейцхак К. Пародонтология: Пер. с нем. под ред. проф. Г.М. Барера, 2-е изд. М.: МЕДпресс-информ; 2014.
- Янушевич О.О. Заболевания пародонта. Современный взгляд на клинико-диагностические и лечебные аспекты. М: ГЭОТАР-Медиа; 2010.
- Пародонтология: Национальное руководство / Под ред. Л.А. Дмитриевой. М.: ГЭОТАР-Медиа; 2013.
- Chambrone L., Chambrone D., Pustiglioni F.E., Chambrone L.A., Lima L.A. Can subepithelial connective tissue grafts be considered the gold standard procedure in the treatment of Miller Class I and II recessiontype defects? J. Dent. 2008; 36: 671-59.
- Chambrone L., Tatakis D.N. Periodontal soft tissue root coverage procedures: A systematic review from the AAP Regeneration Workshop. J. Periodontol. 2015; 86(2): 51-8.
- Cardaropoli D., Tamagnone L., Roffredo A., Gaveglio L. Treatment of gingival recession defects using coronally advanced flap with a porcine collagen matrix compared to coronally advanced flap with connective tissue graft: A randomized controlled clinical trial. J. Periodontol. 2012; 83: 328-1.
- Aroca S., Molnár B., Windisch P. et al. Treatment of multiple adjacent Miller Class I and II gingival recessions with a modified coronally advanced tunnel (MCAT) technique and a collagen matrix or palatal connective tissue graft: A randomized, controlled clinical trial. J. Clin. Periodontol. 2013; 40: @720-13.
- McGuire M.K., Scheyer E.T. Long-Term results comparing xenogeneic collagen matrix and autogenous connective tissue grafts with coronally advanced flaps for treatment of dehiscence-type recession defects. .J. Periodontol. 2016; 87(3): @227-1.
- Buti J., Baccini M., Nieri M., La Marca M., Pini-Prato G.P. Bayesian network meta-analysis of root coverage procedures: Ranking efficacy and identification of best treatment. .J Clin. Periodontol. 2013; 40: 372-86.
- Перова М.Д., Фомичева Е.А., Тропина А.В. Результаты хирургической коррекции рецессии тканей пародонта I и II классов. Новое в стоматологии. М.: 2006; 5(137): 10-4.
- Перова М.Д., Карпюк В.Б., Тропина А.В., Фомичева Е.А., Шубич М.Г. Способ восстановления кости альвеолярного гребня челюсти и тканей с редуцированным регенераторным потенциалом. Патент РФ № 2320285; 2008.
- Лапина Н.В., Скорикова Л.А., Скориков Ю.В. Комплексное лечение мышечно-суставной дисфункции. В кн.: «Сборник научных трудов Общероссийской научно-практической конференции стоматологических кафедр КГМУ и ККООС «Новые технологии в стоматологии». Краснодар, 2007: 162-5.
- Гланц С. Медико-биологическая статистика. М.: Практика; 1998.
- Карпюк В.Б., Перова М.Д., Козлов В.А., Шубич М.Г., Понкина О.Н., Мельник Е.А. Экспериментальная модель реконструкции кости путем остеогенной трансформации аутотрансплантированных свежевыделенных стромальных клеток жировой ткани. Анналы пластической, реконструктивной и эстетической хирургии. 2007; (4): 18-24.
- Любарский М.С., Алтухов И.А., Повещенко О.В., Мустафаев Н.Р., Аглиулин Р.И. Применение стромальных клеток жировой ткани для стимуляции ангиогенеза. В кн.: Материалы IV Всероссийского симпозиума с международным участием: «Актуальные вопросы тканевой и клеточной трансплантологии». Санкт-Петербург, 21-22 апреля 2010 г. СПб.; 2010: 269-73.
- Малаховская В.И. Опыт аутотрансплантации жировой ткани, обогащенной стромально-васкулярной клеточной фракцией, для коррекции дефектов челюстно-лицевой области. Вестник эстетической медицины. 2013; 12(1): 19-25.
- Miller P.D. Jr. A classification of marginal tissue recession. Int. J. Periodont. Rest. Dent. 1985; 5(2): 9.
- Cao Y., Sun Z., Liao L., Meng Y., Han Q., Zhao R.C. Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo. Biochem. Biophys. Res. Commun. 2005; 332(2): 379-80.
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