Synthesis and Study on the Potential Anticancer Activity of Phosphinolinium-Type Halide Salts


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Cytotoxic activity of the newly synthesized phosphinolinium-type bromide salts was evaluated against two cell lines of human origin: A549 lung adenocarcinoma and U251 glioblastoma using the sulforhodamine B assay. Compound with long alkyl chain demonstrate a stronger effect on viability of two cell lines than cysplatin.

作者简介

D. Prokofieva

ZAO “Institute of Experimental Pharmacology”

Email: alexterve@gmail.com
俄罗斯联邦, p/o Kuz’molovskii, str. 245, St. Petersburg, 188663

V. Abzianidze

Chemical Modeling Laboratory, Research Institute of Hygiene, Occupational Pathology and Human Ecology

Email: alexterve@gmail.com
俄罗斯联邦, p/o Kuz’molovskii, St. Petersburg, 188663

A. Bogachenkov

Department of Organic Chemistry, Institute of Chemistry; Department of Organic Chemistry

编辑信件的主要联系方式.
Email: alexterve@gmail.com
俄罗斯联邦, Universitetskii pr. 26, St. Petersburg, 198504; Moskovskii pr. 26, St. Petersburg, 190013

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