Synthesis of New Tetrazole Derivatives and Their Biological Evaluation


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Abstract

An operationally simple and efficient method of synthesis of novel 1,5-disubstituted tetrazoles with high yields from easily accessible 2-(2-benzamido-3-arylacrylamido)acetate under mild conditions is developed. Anticancer and anti-microbial tests of the new tetrazole derivatives have been carried out.

About the authors

H. A. Soliman

Photochemistry Department

Author for correspondence.
Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622

A. Kalmouch

Peptide Chemistry Department

Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622

H. M. Awad

Tanning Materials and Leather Technology Department

Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622

N. A. M. Abdel Wahed

Chemistry of Natural and Microbial Products Department

Email: tarek12_2@yahoo.com
Egypt, Dokki, Cairo, 12622

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