Synthesis of glutaryl-containing derivatives of GRGD and KRGD peptides
- Авторы: Demin A.M.1, Vakhrushev A.V.1, Tumashov A.A.1,2, Krasnov V.P.1
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Учреждения:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Institute of Natural Sciences and Mathematics, Ural Federal University
- Выпуск: Том 68, № 12 (2019)
- Страницы: 2316-2324
- Раздел: Full Articles
- URL: https://bakhtiniada.ru/1066-5285/article/view/243565
- DOI: https://doi.org/10.1007/s11172-019-2705-y
- ID: 243565
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Аннотация
New derivatives of tetrapeptides GRGD (Gly-Arg(Pbf)-Gly-Asp(OMe)-OMe) and KRGD (Boc-Lys-Arg(Pbf)-Gly-Asp(OMe)-OMe) containing a glutaric acid fragment as a linker were synthesized. The linker provides the possibility for binding these derivatives to other biologically active molecules or nanoparticles.
Об авторах
A. Demin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Автор, ответственный за переписку.
Email: demin@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
A. Vakhrushev
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: demin@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
A. Tumashov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Institute of Natural Sciences and Mathematics, Ural Federal University
Email: demin@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990; 19 ul. Mira, Ekaterinburg, 620002
V. Krasnov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: demin@ios.uran.ru
Россия, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
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