Отправить статью по E-mail Hydroxamic acids: synthesis and adjuvant activity in combinatorial anticancer therapy
- Авторы: Fedorov B.S.1, Fadeev M.A.1, Eremeev A.B.1, Konovalova N.P.1, Bogdanov G.N.1, Tatyanenko L.V.1, Sashenkova T.E.1, Mishchenko D.V.1
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Учреждения:
- Institute of Problems of Chemical Physics, Russian Academy of Sciences
- Выпуск: Том 65, № 3 (2016)
- Страницы: 801-805
- Раздел: Full Articles
- URL: https://bakhtiniada.ru/1066-5285/article/view/237682
- DOI: https://doi.org/10.1007/s11172-016-1377-0
- ID: 237682
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Аннотация
Monoand disubstituted N-hydroxyamides of dicarboxylic acids were prepared by reaction of dicarboxylic acids or acid anhydrides with hydroxylamine. The use of these compounds in combinatorial cytostatic therapy of implanted tumors with cisplatin or cyclophosphamide totally inhibits metastasis formation in B16 melanoma and Lewis lung carcinoma, and resulted in 100% survival of leukemic animals.
Об авторах
B. Fedorov
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
M. Fadeev
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
A. Eremeev
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
N. Konovalova
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
G. Bogdanov
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
L. Tatyanenko
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
T. Sashenkova
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
D. Mishchenko
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Россия, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
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