Some aspects of the angiotensin-converting enzyme for leukemias


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The present article shows the diagnosis of different type leukemias in children by the activity of angiotensin-converting enzyme in blood serum to be not promising. Beside that, enalaprilat, carboxylate inhibitor of ACE, exhibited no specific cytotoxic activity against cancer cells; moreover, in the case of chronic myeloleukemia (K-562) and T-cell acute lymphoblastic leukemia (MOLT-4), its weak protective action against cancer cells was noted.

Sobre autores

M. Orlova

Department of Chemistry, M. V. Lomonosov Moscow State University; Dmitry Rogachev Federal Research Center of Pediatric Hematology, Oncology, and Immunology

Autor responsável pela correspondência
Email: orlova.radiochem@mail.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119992; 1 ul. Samory Mashela, Moscow, 117997

A. Orlov

Department of Chemistry, M. V. Lomonosov Moscow State University

Email: orlova.radiochem@mail.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119992

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