Silicon–boron-containing glycerohydrogel having wound healing, regenerative, and antimicrobial activity

Аннотация

A novel combined bioactive silicon–boron-containing glycerohydrogel was prepared by a sol-gel method with the use of silicon and boron glycerolates as precursors. The solid phase of hydrogel was separated by an exhaustive cold extraction and characterized by XRD, atomic emission spectroscopy, IR spectroscopy, and elemental analysis data. Liquid medium of hydrogel was characterized by atomic emission spectroscopy and ¹¹B NMR spectroscopy techniques. The structural features of the hydrogel were studied using transmission electron microscopy; the model of structure was proposed. Silicon–boron-containing hydrogel displays pronounced wound healing, regenerative and antimicrobial activities and could be recommended for more extensive study with the purpose to be applied in medical practice.