LEVEL OF MATRIX METAL PROTEINAS AND THEIR TISSUE INHIBITORS IN WOMEN WITH NON-CARE OF PREGNANCY
- 作者: Tulupova M.S.1, Hamoshin M.B.1, Nevezhkina T.A.2, Sidorova O.N.2
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隶属关系:
- FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation
- Pacific State Medical University, Ministry of Health of the Russian Federation
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 581-583
- 栏目: ORIGINAL ARTICLES
- URL: https://bakhtiniada.ru/1028-7221/article/view/120308
- DOI: https://doi.org/10.31857/S102872210006981-4
- ID: 120308
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详细
Surveyed 28 patients with sexually transmitted infections (STIs), or papillomavirus infection (PVI). The patients were divided into the main group (FG) and the control group (GC) (n = 10). The main group was divided into 2 groups: Group I (n = 8) ‒ STIs with MWI, Group II (n = 10) ‒ STIs without MWI. A simultaneous increase in MMP-9 and TIMP-1 in the serum of women with miscarriage was established, which indicates the role of the processes of damage to the extracellular matrix in its pathogenesis. Diff erences in the ratio of MMP-9 to TIMP-1 depending on the presence of HPV were revealed. Women with STIs without HPV are dominated by products of TIMP that can have a profibrinogenic eff ect.
作者简介
M. Tulupova
FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation
Email: fake@neicon.ru
Ph.D., Doctoral Candidate of the Department of Obstetrics and Gynecology with a course of Perinatology,
Vladivostok
俄罗斯联邦M. Hamoshin
FGOAO HE “Russian University of Peoples’ Friendship” of the Ministry of Education of the Russian Federation
Email: fake@neicon.ru
MD, Professor of the Department of Obstetrics and Gynecology with a course in Perinatology,
Vladivostok
俄罗斯联邦T. Nevezhkina
Pacific State Medical University, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: www.tanya.ru9292@mail.ru
Post-Graduate Student, Department of Normal and Pathological Physiology,
Vladivostok
俄罗斯联邦O. Sidorova
Pacific State Medical University, Ministry of Health of the Russian Federation
Email: fake@neicon.ru
Ph.D., Associate Professor, Department of Normal and Pathological Physiology,
Vladivostok
俄罗斯联邦参考
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- Петров Ю. А., Алехина А. Г., Блесманович А. Е. Беременность, роды, состояние плода и новорожденного у матерей с папилломавирусной инфекцией // Современные проблемы науки и образования. – 2018. – № 2 – С. 22.
- Машкина Е. В., Коваленко К. А., Мараховская Т. А., Сараев К. Н., Беланова А. А., Шкурат Т. П. Исследование ассоциации полиморфных вариантов генов матриксных металлопротеиназ с репродуктивными потерями в I триместре беременности // Генетика. 2016, 52; № 8, 958–965.
- Kapral M., Wawszczyk J., Jurzak M., Hollek A., Węglarz L. The effect of inositol hexaphosphate on the expression of selected metalloproteinases and their tissue inhibitors in IL-1β-stimulated colon cancer cells // International Journal of Colorectal Disease. 2012. 27;11. 1419–1428.
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