EFFECTS OF CARBOPLATIN WITH CUCURBIT[7]URIL ON SUBPOPULATION COMPOSITION AND PROLIFERATIVE ACTIVITY OF LYMPHOCYTES IN VITRO
- 作者: Pashkina E.A.1,2, Aktanova A.A.2, Ermakov A.A.2, Knauer N.Y.1, Mirzaeva I.V.3, Kovalenko E.A.3
-
隶属关系:
- FSBSI “Research Institute of Fundamental and Clinical Immunology”
- Novosibirsk State Medical University
- Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 462-464
- 栏目: ORIGINAL ARTICLES
- URL: https://bakhtiniada.ru/1028-7221/article/view/120261
- DOI: https://doi.org/10.31857/S102872210006930-8
- ID: 120261
如何引用文章
全文:
详细
It is known that the use of delivery systems can reduce the toxicity of platinum compounds without losing a high therapeutic effect. In this work, the immunotoxic effect of carboplatin when co-added with cucurbit[7]uril was investigated, including the effect on the subpopulation composition of lymphocytes and their proliferative activity in vitro.
作者简介
E. Pashkina
FSBSI “Research Institute of Fundamental and Clinical Immunology”;Novosibirsk State Medical University
编辑信件的主要联系方式.
Email: pashkina.e.a@yandex.ru
PhD, Researcher, Clinical Immunopathology Laboratory;
Assistant of the Department of Clinical Immunology at the Medical Faculty,
Novosibirsk
俄罗斯联邦A. Aktanova
Novosibirsk State Medical University
six-year student of the Faculty of Medicine and Prevention of the specialty of Medical Biophysics,
Novosibirsk
俄罗斯联邦A. Ermakov
Novosibirsk State Medical University
six-year student of the Faculty of Medicine and Prevention of the specialty of Medical Biophysics,
Novosibirsk
俄罗斯联邦N. Knauer
FSBSI “Research Institute of Fundamental and Clinical Immunology”
PhD student, Clinical Immunopathology Laboratory,
Novosibirsk
俄罗斯联邦I. Mirzaeva
Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences
PhD, Researcher, Laboratory of Condensed Matter Physical Chemistry,
Novosibirsk
俄罗斯联邦E. Kovalenko
Institute of Inorganic Chemistry of the Siberian Branch of the Russian Academy of Sciences
PhD, Researcher, Laboratory of cluster and supramolecular chemistry,
Novosibirsk
俄罗斯联邦参考
- Wheate N. J. Improving platinum (II)-based anticancer drug delivery using cucurbit [n] urils. Journal of inorganicbiochemistry. 2008, 102, 2060–2066.
- Mirzaeva I. V., Moroz N. K., Andrienko I. V., Kovalenko E. A. Interaction between carboplatin and cucurbit[7]uril studied by means of multinuclear NMR spectroscopy and DFT calculations J. Mol. Struct. 2018, 1163, 68–76.
- Актанова А. А., Ермаков А. А., Пашкина Е. А. Сравнительный анализ противоопухолевого и иммунотоксического действия комплекса кукурбит[7] урила с карбоплатином. Российский иммунологический журнал. 2018, 12(21), 595–597.
补充文件
