STUDY OF THE BIOLOGICAL AND MECHANICAL PROPERTIES OF THE ULTRA-HIGH-MOLECULAR-WEIGHT-POLY-ETHYLENE COMPOSITE FOR EMPLOYMENT AS CARTILAGE BIOIMPLANT
- 作者: Kiselevsky M.V.1, Anisimova N.Y.1, Lebedinskaya O.V.2, Kopylov A.N.1
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隶属关系:
- NN Blokhin Scientifi c Institutе “Russian Cancer Research Center”
- Acad. EA Wagner Perm State Medical University
- 期: 卷 20, 编号 2 (2017)
- 页面: 347-350
- 栏目: Articles
- URL: https://bakhtiniada.ru/1028-7221/article/view/120151
- ID: 120151
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Aim of this study is researching the biological and mechanical features of the material, made of ultra-high-molecular-weight-poly-ethylene(UHMWPE) Studing the mechanical features showed that the material prepared with addition of Al2O3 and with using mechanical activation has the highest mechanical features, wear resistance in particular, in comparison with UHMWPE samples without Al2O3 or prepared without mechanical activation. was chosen for. After 60 days orthotopical transplantation this material in rats we did not fined signs of inflammation, cellular infiltration, destruction of material or bone-cartilage defect. Sample was in position of implantation without any shifts. Acquired data shows the perspective-ness of UHMWPE as a material for creating bioimplants for cartilage defects replacement.
作者简介
M. Kiselevsky
NN Blokhin Scientifi c Institutе “Russian Cancer Research Center”
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Email: noemail@neicon.ru
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N. Anisimova
NN Blokhin Scientifi c Institutе “Russian Cancer Research Center”
Email: noemail@neicon.ru
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O. Lebedinskaya
Acad. EA Wagner Perm State Medical University
Email: noemail@neicon.ru
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A. Kopylov
NN Blokhin Scientifi c Institutе “Russian Cancer Research Center”
Email: noemail@neicon.ru
俄罗斯联邦
参考
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- UHMWPE biomaterials handbook Steven M. Kurz - 2009.
- Исследование биосовместимости и иммуногенности синтетических имплантатов / Копылов А. Н., Лебединская О. В., Анисимова Н. Ю., Сенатов Ф. С., Максимкин А. В., Киселевский М. В. // Российский иммунологический журнал.-2013.- Т. 7.- № 2-3.- С. 304-305.
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