COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR 9 AGONIST ON RECEPTOR FUNCTION OF MONOCYTES IN NORMAL AND INFECTIOUS PROCESS
- 作者: Rusinova T.V.1, Kolesnikova N.V.1, Chudilova G.A.1, Filippov E.F.1, Kaplina E.N.1
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隶属关系:
- Kuban state medical university
- 期: 卷 20, 编号 3 (2017)
- 页面: 485-487
- 栏目: Articles
- URL: https://bakhtiniada.ru/1028-7221/article/view/119793
- ID: 119793
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详细
Comparative evaluation of character of the expression of TLR 9, CD11b and CD14 receptors monocytes whole blood under the influence of Derinat and synthetic TLR 9 ligand in healthy individuals and in acute infectious diseases of viral and bacterial origin has been studied. It has been shown that the unidirectional effects of study drugs relate changes in the number of monocytes only in groups with infectious process. Differently directed effects identified in relation to expression of molecules QD11b monocytes in all groups.
作者简介
T. Rusinova
Kuban state medical university
编辑信件的主要联系方式.
俄罗斯联邦
N. Kolesnikova
Kuban state medical university俄罗斯联邦
G. Chudilova
Kuban state medical university俄罗斯联邦
E. Filippov
Kuban state medical university俄罗斯联邦
E. Kaplina
Kuban state medical university俄罗斯联邦
参考
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- Lindau D., Musserd J., Wagner B. J. Primary blood neutrophils a functional cell surface Toll-like receptor 9 / D. Lindau, J. Musserd, B. J. Wagner // Europ.J.of Immunology.- 2013.- V.43(8).- P 2101-2113.
- Федянина Л. Н. Влияние дезоксирибонуклеиновой кислоты из молок лососевых рыб на секрецию цитокинов клетками крови здоровых доноров / Л. Н. Федянина // Мед.иммунол.-2005.- Т. 7. № 5-6.- С. 617-619.
- Expression of Toll-like receptors 2 and 9 in cells of dog jejunum and colon naturally infected with Leish-mania infantum / M. M Figueiredo, I. FG.Amorim, A. JW. Pinto. et al. // BMC Immunol. - 2013.- 14(22). doi: 10.1186/1471-2172-14-22.
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