ANTIGENPRESENTAL FUNCTION OF B-CELLS IN PATIENTS WITH REMITTING MULTIPLE SCLEROSIS
- Authors: Sursyakova N.V.1, Kuklina E.M.2, Baydina T.V.1
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Affiliations:
- Federal State Educational Institution of Higher Education “Perm State Medical University named after Academician E. A. Vagner" of the Ministry of Health of the Russian Federation
- Federal State Institution of Science Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences
- Issue: Vol 20, No 3 (2017)
- Pages: 519-521
- Section: Articles
- URL: https://bakhtiniada.ru/1028-7221/article/view/119910
- ID: 119910
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Abstract
The antigen-presenting function of B-lymphocytes in patients with a remitting form of multiple sclerosis was studied. It was found that B cells in the presentation of different antigens have a different ability to induce differentiation of naive T cells in Th17 and Treg. A new mechanism for activating the differentiation of naive T cells in Th17 in the presentation of autoantigens with B cells in multiple sclerosis has been suggested.
About the authors
N. V. Sursyakova
Federal State Educational Institution of Higher Education “Perm State Medical University named after Academician E. A. Vagner" of the Ministry of Health of the Russian Federation
Author for correspondence.
Email: noemail@neicon.ru
Russian Federation
E. M. Kuklina
Federal State Institution of Science Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences
Email: noemail@neicon.ru
Russian Federation
T. V. Baydina
Federal State Educational Institution of Higher Education “Perm State Medical University named after Academician E. A. Vagner" of the Ministry of Health of the Russian Federation
Email: noemail@neicon.ru
Russian Federation
References
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