Disturbances of cerebral circulation in primary antiphospholipide syndrome and sneddon’s syndrome

66 patients with Sneddon’s syndrome and 29 patients with primary antiphospholipide syndrome has been examinated. Clinical picture of Sneddon’s syndrome was characterized by combination of cerebrovascular disturbances (ischemic disturbance of cerebral circulation, primary disturbance of cerebral circulation) with skin change in the form of livedo. In some patients there were thromboses of peripheric veins, ischemic heart disease, spontaneous abortions or intrauterine fetus death in women, thrombocytopenia. In 64% of patients with Sneddon’s syndrome there were revealed antibodies to phospholipids — cardiolipin and/or lupus anticoagulant, and this indicates that these cases belong to primary antiphospholipide syndrome. Clinical manifestations in 29 patients with primary antiphospholipide syndrome were similar to those in Sneddon’s syndrome except for the absence of livedo.