Pagetoid reticulosis
- 作者: Sergeeva E.Y.1, Khorzhevskii V.A.1, Ruksha T.G.1
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隶属关系:
- Krasnoyarsk State Medical University
- 期: 卷 97, 编号 6 (2021)
- 页面: 81-86
- 栏目: GUIDELINES FOR PRACTITIONERS
- URL: https://bakhtiniada.ru/0042-4609/article/view/117588
- DOI: https://doi.org/10.25208/vdv1239
- ID: 117588
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详细
Pagetoid reticulosis (PR) is a rare type of mycosis fungoides. Clinical symptoms of PR can mimic other skin diseases of papulosquamous, neoplastic, and infectious origin that hampers PR diagnostics. The main histopathologic feature of PR is dense intraepidermal infiltration by medium to large-size lymphocytes through the epidermis leading to pagetoid plaque formation. There are three common immunophenotypes of PR: CD4-positive T-helper phenotype (CD3+, CD4+, CD8–); T-cytotoxic/suppressor (CD3+, CD4–, CD8+); and double negative phenotype (CD3+, CD4–, CD8–). The clinical case of PR with rare immunophenotype (CD2+, CD3+, CD8+ lymphoid infiltrate) is presented. The careful analysis of the symptoms, pathomorphological and immunohistochemical data is necessary for accurate PR diagnostics.
作者简介
Ekaterina Sergeeva
Krasnoyarsk State Medical University
Email: e.ya.sergeeva@mail.ru
ORCID iD: 0000-0002-2089-6022
к.м.н.
俄罗斯联邦, Partizana Zheleznyaka str., 1, 660022, KrasnoyarskVladimir Khorzhevskii
Krasnoyarsk State Medical University
Email: vladpatholog@yandex.ru
ORCID iD: 0000-0002-9196-7246
MD, Cand. Sci. (Med.)
俄罗斯联邦, Partizana Zheleznyaka str., 1, 660022, KrasnoyarskTatiana Ruksha
Krasnoyarsk State Medical University
编辑信件的主要联系方式.
Email: tatyana_ruksha@mail.ru
ORCID iD: 0000-0001-8142-4283
MD, Dr. Sci. (Med.), Professor
俄罗斯联邦, Partizana Zheleznyaka str., 1, 660022, Krasnoyarsk参考
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