4-amino-2-phenylindole-based compounds with potential antibacterial activity


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Primary condensation of 4-amino-2-phenylindole with ethyl acetoacetate and 4,4,4-trifluoroacetoacetate resulted in corresponding amides, which under acidic conditions were converted to pyrrolo[2,3-h]quinolones. Antibacterial activity of the amide obtained from aminoindole and ethyl 4,4,4-trifluoroacetylacetate was detected.

作者简介

E. Alyamkina

Evsev’ev Mordovia State Pedagogical Institute

Email: ymar@org.chem.msu.ru
俄罗斯联邦, Saransk, 430007

I. Stepanenko

Ogarev Mordovia State University

Email: ymar@org.chem.msu.ru
俄罗斯联邦, Saransk, 430005

S. Yamashkin

Evsev’ev Mordovia State Pedagogical Institute

Email: ymar@org.chem.msu.ru
俄罗斯联邦, Saransk, 430007

M. Yurovskaya

Department of Chemistry

编辑信件的主要联系方式.
Email: ymar@org.chem.msu.ru
俄罗斯联邦, Moscow, 119991

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